Join us on May 5th for the next William K. Warren, Jr. Frontiers in Neuroscience Lecture!🧠
​
LIBR is pleased to welcome Dr. Thomas E. Nichols, Professor of Neuroimaging Statistics at the University of Oxford Big Data Institute, who will present "New Approaches to Modeling Longitudinal Neuroimaging data." The lecture runs from 12:00–1:00 PM in the LPCH auditorium and is approved for 1 CE credit hour across multiple disciplines, including physicians, psychologists, social workers, CADCs/LADCs, and LPCs/LMFTs. Visit the link for more details!

​https://www.laureateinstitute.org/news/may-wkw-frontiers-in-neuroscience-lecture-series-dr-thomas-e-nichols

The 2025 Laureate Institute for Brain Research (LIBR) Annual Report is now available to download via the link below. The report highlights the past year at LIBR, including a message from President and Scientific Director, Dr. Martin Paulus, updates on current research areas, and an overview of key initiatives and accomplishments.
​
This year’s report also features progress in areas such as treatment-resistant depression, neuromodulation, and large-scale population studies, as well as continued efforts to integrate neuroscience, data science, and clinical research. Readers will also find information on collaboration, training programs, select publications, and opportunities to participate in research.

We hope you enjoy this year’s publication and appreciate your continued interest in LIBR’s work to advance mental health through science in 2026 and beyond.

Dr. Thomas E. Nichols - May 5, 2026

"New Approaches to Modeling Longitudinal Neuroimaging Data"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program in the LPCH auditorium  

Thomas Nichols is the Professor of Neuroimaging Statistics at the University of Oxford Big Data Institute. He is a statistician with a solitary focus on modelling and inference methods for brain imaging research. He has both industrial and academic experience and a diverse training including computer science, cognitive neuroscience and statistics. He was the Director Modelling and Genetics at GlaxoSmithKline's Clinical Imaging Centre, London, and has been at Oxford since 2017. The focus of his work is developing modelling and inference methods for brain image data, specifically Magnetic Resonance Imaging (MRI) and functional MRI.  His current work includes methodology for population scale neuroimaging data, longitudinal studies and neuroimaging genetics.

 Learning objectives:  

1. Identify the key differences between longitudinal and cross-sectional models.
2. Compare the strengths and weakness of the sandwich estimator vs. linear mixed effects model approach.
3. List two different approaches to modeling binary-valued lesion map data.

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists recognizes AMA PRA Category 1 credit(s)™. Saint Francis Health System is accredited by the OSMA.
 
For Social Workers: Saint Francis Health System is an approved CE Provider for the Oklahoma State Board of Licensed Social Workers.  This event if approved for 1 hours, Category 1 Clinical.  (CEP Number - 20260007)

For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors.      (1 hour) (Provider Number - 20260008)
 
The LPC/LMFT Saint Francis Health System is a Board approved CE Provider for the State Board of Behavioral Health Licensure (BBHL). This course is approved for 1 hour of CE.

For questions, email:  Ally Deatherage at [email protected]

Dr. Laurence J. Kirmayer - April 7, 2026

"The Situated Brain:  A Cultural Ecosocial Approach"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program VIA ZOOM ONLY (See link below)

Join Zoom Meeting
https://laureateinstitute-org.zoom.us/j/87982248899
Meeting ID: 879 8224 8899
Passcode: 201016

Laurence J. Kirmayer, MD, FRCPC, FCAHS, FRSC is Distinguished James McGill Professor and Director of the Division of Social and Transcultural Psychiatry, Department of Psychiatry, McGill University. He is a Senior Investigator at the Lady Davis Institute, and Director of the Culture & Mental Health Research Unit at the Institute of Community and Family Psychiatry, Jewish General Hospital in Montreal, where he conducts research on culturally responsive mental health services, the mental health of Indigenous peoples, the integration of culture in global mental health, psychiatric anthropology, and the philosophy of psychiatry. He founded and directs the annual McGill Summer Program in Social and Cultural Psychiatry (www.mcgill.ca/tcpsych). In Canada, he founded the national Network for Aboriginal Mental Health Research (www.namhr.ca), the Cultural Consultation Service (www.mcgill.ca/ccs), and the Multicultural Mental Health Resource Centre (www.mmhrc.ca). His publications include: Healing and the Invention of Metaphor: Toward a Poetics of Illness Experience, (Cambridge University Press, 2025); Unraveling the World Knot: Mind-Body Problems in Clinical Practice (Cambridge, 2026) and the co-edited volumes: Understanding Trauma: Integrating Biological, Clinical and Cultural Perspectives (Cambridge University Press, 2007); Healing Traditions: The Mental Health of Aboriginal Peoples in Canada (University of British Columbia Press, 2009); Cultural Consultation: Encountering the Other in Mental Health Care (Springer, 2014); Re-Visioning Psychiatry: Cultural Phenomenology, Critical Neuroscience, and Global Mental Health (Cambridge, 2015); and Culture, Mind and Brain: Emerging Concepts, Models, and Applications (Cambridge, 2020). He is a Fellow of the Canadian Academy of Health Sciences and the Royal Society of Canada (Academy of Social Sciences).

  Learning Objectives:  

1. To describe how a cultural-ecosocial framework conceptualizes the brain as situated in social, cultural, and structural contexts, and explain why this challenges reductionistic biomedical models.
2. Formulate research questions and study designs that operationalize a cultural-ecosocial perspective, including measures of social determinants, cultural meaning-making, and brain-related processes, in order to investigate how context shapes mechanisms and outcomes in mental health.
3. Apply cultural-ecosocial principles to design or critique psychiatric interventions and services that integrate neurobiological, psychological, social, and cultural levels of care in a coherent clinical or programmatic approach.

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists recognizes AMA PRA Category 1 credit(s)™. Saint Francis Health System is accredited by the OSMA.
 
For Social Workers: Saint Francis Health System is an approved CE Provider for the Oklahoma State Board of Licensed Social Workers.  This event if approved for 1 hours, Category 1 Clinical.  (CEP Number - 20260007)

For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors. (1 hour) (Provider Number - 20260008)
 
The LPC/LMFT Saint Francis Health System is a Board approved CE Provider for the State Board of Behavioral Health Licensure (BBHL). This course is approved for 1 hour of CE.

For questions, email:  Ally Deatherage at [email protected]

Dr. Alan F. Schatzberg - March 3, 2026

"Understanding the Opioid Effects of Ketamine" 

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program in the LPCH auditorium  

ALAN F. SCHATZBERG, MD, received his MD from NYU in 1968. He completed his psychiatric residency at the Massachusetts Mental Health Center and a clinical fellowship in psychiatry at Harvard Medical School. After serving in the United States Air Force, he joined the staff at McLean Hospital and served in several leadership positions there. He became Clinical Director of the Massachusetts Mental Health Center and Professor of Psychiatry at Harvard Medical School, while continuing his research program at McLean Hospital on the biology/treatment of depression. In 1991, Dr. Schatzberg became the Kenneth T. Norris, Jr., Professor and Chairman of the Department of Psychiatry and Behavioral Sciences at Stanford University, where he served as chair until 2010. He now directs the Stanford Mood Disorders Center. Dr. Schatzberg has been an active investigator in the biology and psychopharmacology of depressive disorders. He has authored over 700 publications and abstracts.  He is the Co-Author of the Manual of Clinical Psychopharmacology in its 10th Edition (2024) and has co-edited the Textbook of Psychopharmacology (Sixth Edition, 2024). He has been president of the American Psychiatric Association (APA), the American College of Neuropsychopharmacology (ACNP), and the Society of Biological Psychiatry (SOBP). He has received numerous awards for excellence and leadership from the APA, ACNP, SOBP, Max Planck Psychiatric Institute, Brain and Behavior Foundation, Anna Monika Foundation, U. Pennsylvania, Weill Cornell Medical College, etc.  He has three honorary doctorates.  He is a member of the National Academy of Medicine and is their 2025 Sarnat Prize recipient. 

  Learning objectives:  

1. Review preclinical data on ketamine mechanisms of action.
2. Review studies demonstrating opioid properties of ketamine in man.
3. Discuss significance of mechanisms of action to risk/benefit ratio.

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists recognizes AMA PRA Category 1 credit(s)™. Saint Francis Health System is accredited by the OSMA.
 
For Social Workers: Saint Francis Health System is an approved CE Provider for the Oklahoma State Board of Licensed Social Workers.  This event if approved for 1 hours, Category 1 Clinical.  (CEP Number - 20260007)

For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors.      (1 hour) (Provider Number - 20260008)
 
The LPC/LMFT Saint Francis Health System is a Board approved CE Provider for the State Board of Behavioral Health Licensure (BBHL). This course is approved for 1 hour of CE.

For questions, email:  Ally Deatherage at [email protected]

Dr. Nancy Zucker - February 3, 2026

"The Detection and Phenomenology of ARFID:  Considerations to Guide Treatment Selection"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program in the LPCH auditorium  

Nancy Zucker is a Professor of Psychiatry and Behavioral Sciences and Psychology and Neuroscience at Duke University and Founder and Director of the Duke Center for Eating Disorders. Nancy uses our growing understanding of interoception to develop interventions that help young people trust their bodies.

  Learning objectives:  

1. List the diagnostic criteria of Avoidant/Restrictive Food Intake Disorder.
2. Describe and define three different drivers of food avoidance and/or restriction on ARFID.
3. List the emotional drivers of food avoidance in a client with ARFID and match different treatment modules to that specific clinical presentation.

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists recognizes AMA PRA Category 1 credit(s)™. Saint Francis Health System is accredited by the OSMA.
 
For Social Workers: Saint Francis Health System is an approved CE Provider for the Oklahoma State Board of Licensed Social Workers.  This event if approved for 1 hours, Category 1 Clinical.  (CEP Number - 20260007)

For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors.      (1 hour) (Provider Number - 20260008)
 
The LPC/LMFT Saint Francis Health System is a Board approved CE Provider for the State Board of Behavioral Health Licensure (BBHL). This course is approved for 1 hour of CE.

For questions, email:  Ally Deatherage at [email protected]

​Our President & Scientific Director, Dr. Martin Paulus, has been named a Highly Cited Researcher — placing him among the top 1% of faculty and researchers worldwide over the past decade.

​This distinction from Clarivate recognizes researchers whose work shapes their fields and drives meaningful impact across the globe.

We’re proud to celebrate Dr. Paulus and the innovative research happening at LIBR every day.

Join us in congratulating him on this incredible achievement!

Dr. Mark A. Frye - January 6th, 2026

"Collaborations Fostering Precision Medicine & Health Care Delivery in Bipolar Disorder & Major Depression"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program in the LPCH auditorium  

Mark A. Frye, M.D., is a Consultant in the Department of Psychiatry & Psychology at Mayo Clinic. He is the past Chair of the Department of Psychiatry & Psychology (2010-2020) and is recognized with the distinction of the Stephen and Shelley Jackson Family Professorship in Individualized Medicine.
Born and raised in Rochester, Dr. Frye received his M.D. from the University of Minnesota and completed his psychiatric training at the Semel Institute for Neuroscience and Human Behavior at the David Geffen School of Medicine at UCLA. He subsequently completed a fellowship at the National Institute of Mental Health in Bethesda, Maryland with a research focus on the neurobiology of treatment resistant depression and bipolar disorder.

Dr. Frye and his team established the Mayo Clinic Individualized Medicine Biobank for Bipolar Disorder to identify the underpinning mechanisms of bipolar disorder through genomic studies. An active clinical investigator, he has received research support from NIMH, NIAAA, Mayo Foundation, Brain & Behavior Research Foundation, and industry partners, and has published more than 500 peer-reviewed papers.
 
He has received numerous awards including the American College of Psychiatry Mood Disorders Research Award (2018), Gerald Klerman Senior and Young Investigator Awards from the Depression Bipolar Alliance (2014, 2003), the  International Society for Bipolar Disorder Robert Post MD Mentoring Award (2022) and Mogens Schou Education Award (2011),  2 Mayo Clinic Rome Mentorship Awards (2011, 2012), and  3 UCLA departmental medical student and resident teaching awards (1994, 2003, 2005).
 
Dr. Frye is a Scientific Chair for Breakthrough Discoveries for thriving with Bipolar Disorder (BD2), a research foundation committed to building a large scale longitudinal cohort embedded within a learning health network to facilitate new knowledge that rapidly drives  improvement in clinical care. He is also the  President of the National Network of Depression Centers (NNDC), a network collaborating in clinical innovation, research, and education and Scientific Advisory Board Chair of the Depression Bipolar Support Alliance (DBSA), a leading national organization mission driven to improve the lives of people who live with mood disorders.
 
 Learning objectives:  

1. Recognize how measurement-based care can drive practice innovation.
2. Appreciate how collaborative groups are positioned to close health care gaps.
3. Understand impact of providing greater precision to existing pharmacotherapy for mood disorders.

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists recognizes AMA PRA Category 1 credit(s)™. Saint Francis Health System is accredited by the OSMA.
 
For Social Workers: Saint Francis has submitted a request for approval to the Oklahoma State Board of Licensed Social Workers.

For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors.      (1 hour) (Provider Number - 20260008)
 
The LPC/LMFT Saint Francis Health System is a Board approved CE Provider for the State Board of Behavioral Health Licensure (BBHL). This course is approved for 1 hour of CE.

For questions, email: Ally Deatherage at [email protected]