THE PAULUS LABORATORY
Martin Paulus, M.D.Scientific Director and President, Laureate Institute for Brain Research
Curriculum Vitae Email: mpaulus@laureateinstitute.org | Phone: 918-502-5120
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Scientific Background
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Dr. Paulus studied Medicine at the Johannes Gutenberg University in Mainz from 1979-1985. He received a postdoctoral fellowship from the Deutsche Forschungsgemeinschaft (German Research Foundation) in 1986 to study the effects of calcium antagonists on animal models of mania at the University of California San Diego (UCSD). In 1993, Dr. Paulus left UCSD to resume his medical training and completed his internship at the Long Island Jewish Medical Center/Zucker Hillside Hospital on Long Island, NY. In 1994, he rejoined the Department of Psychiatry at UCSD as a psychiatric resident. Dr. Paulus completed his residency in psychiatry in 1997. At that time, he joined the Department of Psychiatry at UCSD as an Assistant Professor and became a staff psychiatrist at the Veterans Affairs San Diego Health Care System (VASDHS). In May 2014, Dr. Paulus joined the Laureate Institute for Brain Research (LIBR) in Tulsa, OK, as the Scientific Director and President.
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Dr. Paulus has published over 300 scientific papers, has been funded continuously by federal grants since 1997, and is currently the Principal Investigator on an NIGMS CoBRE grant to develop an infrastructure for young investigators to establish their research careers with NIH competitive funding. Moreover, Dr. Paulus is a Co-PI on an ABCD Site U01 grant to test behavior and brain function of approximately 700 children ages 9-10 in the Tulsa area and to follow these children and their families for the next 10 years. He has served on numerous research panels, study sections, and advisory committees. Currently, Dr. Paulus is conducting a large-scale study in Tulsa, the T-1000, to determine whether biological measures can be developed to help a clinician predict patient outcomes. Dr. Paulus is also a member of the Adolescent Brain Cognitive Development (ABCD) study, which aims to determine how the brain changes during the course of adolescence and how these changes put adolescents at risk for substance use.
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Lab Members
Kai Ping Burrows, Ph.D.
Staff Scientist Volunteer Faculty Member, Department of Nutritional Sciences, University of Oklahoma |
Katie Forthman
Data Scientist |
Leandra Figueroa-Hall, Ph.D.
Post-Doctoral Research Associate |
Rayus Kuplicki, Ph.D.
Lead, Data Analyst Volunteer Faculty Member, Health Sciences Center, University of Oklahoma |
Matt Moradi, Ph.D.
Graduate Student, TU |
Philip Spechler, Ph.D.
Post-Doctoral Research Associate |
Bohan Xu
Researcher |
Haixia Zheng, Ph.D.
Post-Doctoral Research Associate |
Ongoing Studies
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Tulsa 1000: Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
Study Goal: To determine the relationship between factors that assess emotion, cognition, reward and interoception in mood, anxiety, eating and substance use disorders such that these factors can be used to generate predictors of treatment outcome response in clinical settings. Neuroscience-Based Mental Health Assessment and Prediction (NeuroMAP)- Center of Biomedical Research Excellence (CoBRE)
Study Goal: NeuroMAP aims to provide a (a) scientific, (b) operational, and (c) educational infrastructure for innovative neuroscience-based research to use individual differences on several biological levels together with sophisticated statistical approaches to generate clinically meaningful predictions of risk and outcomes for mood, anxiety, and eating disorders. To participate in a study, please call 918-502-5100 or email info@laureateinstitute.org |
Selected Publications
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Victor TA, Khalsa SS, Simmons WK, et al. Tulsa 1000: A Naturalistic Study Protocol for Multilevel Assessment and Outcome Prediction in a Large Psychiatric Sample. BMJ Open. 2018;8(1):e016620.
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Ball TM, Stein MB, Ramsawh HJ, Campbell-Sills L, Paulus MP. Single-Subject Anxiety Treatment Outcome Prediction using Functional Neuroimaging. Neuropsychopharmacology. 2018;43(4):926.
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Paulus MP. Evidence-Based Pragmatic Psychiatry-A Call to Action. JAMA Psychiatry. 2017.
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Huang H, Thompson W, Paulus MP. Computational Dysfunctions in Anxiety: Failure to Differentiate Signal From Noise. Biol Psychiatry. 2017;82(6):440-446.
Squeglia LM, Ball TM, Jacobus J, et al. Neural Predictors of Initiating Alcohol Use During Adolescence. Am J Psychiatry. 2016:appi.ajp.2016.15121587.
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Gowin JL, May AC, Wittmann M, Tapert SF, Paulus MP. Doubling down: Increased Risk-taking Behavior Following a Loss by Individuals with Cocaine Use Disorder is Associated with Striatal and Anterior Cingulate Dysfunction. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2017;2(1):94-103.
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Ekhtiari H, Rezapour T, Aupperle RL, Paulus MP. Neuroscience-informed Psychoeducation for Addiction Medicine: A Neurocognitive Perspective. Progress in Brain Research. 2017;235:239-264.
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Research Collaborators
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Marc Wittmann, Ph.D.
Institut für Grenzgebiete der Psychologie und Psychohygiene Tony Yang, M.D., Ph.D.
University of California- San Francisco Lawrence Frank, Ph.D.
University of California- San Diego Alan N Simmons, Ph.D.
University of California- San Diego Wesley R Thompson, Ph.D.
University of California- San Diego |
Michelle Craske, Ph.D.
University of California- Los Angeles Gregory Brown, Ph.D.
University of California- San Diego Walter Kaye, M.D.
University of California- San Diego Murray B Stein, M.D., M.P.H., F.R.C.P.C
University of California- San Diego Lindsay M. Squeglia, Ph.D.
Medical University of South Carolina |
Greg Fonzo, Ph.D.
Stanford University Paul Davenport, Ph.D.
University of Florida James Fowler, Ph.D.
University of California- San Diego Tom T Liu, Ph.D.
University of California- San Diego Susan F Tapert, Ph.D.
University of California- San Diego Angela Yu, Ph.D.
University of California- San Diego |
