May WKW Frontiers in Neuroscience Lecture Series: Dr. Steve Brohawn

Dr. Paul Holtzheimer - April 2, 2024

"Mechanosensitive Potassium Channels in Nerves: Molecular Mechanisms, Disease Relevance, and Potential Targets for Neuromodulation"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
12:00 pm - 1:00 pm     Program in the LPCH auditorium  

Dr. Steve Brohawn is an Associate Professor at the University of California, Berkeley in the Department of Molecular and Cell Biology and the Helen Wills Neuroscience Institute. Research in his laboratory is focused on understanding the molecular basis of sensory transduction and electrical signaling in the nervous system. To this end, the lab uses a combination of cryo-electron microscopy and electrophysiology to investigate the structure and function of membrane protein ion channels and transporters. Prior to starting his laboratory in 2016, Dr. Brohawn was a Helen Hay Whitney Postdoctoral Fellow in Dr. Rod MacKinnon’s lab at the Rockefeller University from 2010 to 2015 where he studied ion channels that sense mechanical force. Steve received his PhD in Biology in 2010 from the Massachusetts Institute of Technology where he worked with Dr. Thomas Schwartz on the structure and function of the nuclear pore complex. He received his B.S. from the University of Delaware in 2004 where he worked with Dr. Colin Thorpe on the enzymology of oxidative protein folding. Work in his lab has been recognized with a NIH New Innovator Award, a New York Stem Cell Neuroscience Investigator Award, a Sloan Research Fellowship, a McKnight Neuroscience Scholar Award, and a Klingenstein-Simons Research Fellowship.

Learning objectives:  

1. Mechanosensitive potassium channel structure and function in nerves and white matter.
2. Basis for disease causing mutations in mechanosensitive potassium channels.     
3. Mechanisms of ion channel ultrasound sensitivity and potential applications for neuromodulation.
   ​
   

For Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to provide continuing medical education for physicians.
Saint Francis Health System designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
For Psychologists: The Oklahoma State Board of Examiners of Psychologists, the American Psychological Association and the Oklahoma Psychological Association recognize AMA PRA Category 1  credit™. Saint Francis Health System is accredited by the OSMA
 
For Social Workers: An application has been sent to the Oklahoma State Board of Licensed Social Workers for 1 hour Category 1 Clinical. 
 
For CADCs and LADCs Saint Francis Health System is accredited as a provider of continuing education programs for CADCs and LADCs through the Oklahoma Board of Licensed Alcohol and Drug Counselors.      (1 hour)
 
The LPC/LMFT This event as been approved by the State Board of Behavioral Health Licensure (BBHL) for 1 hour of CE.  

For questions , email:  Lauren Haguewood at [email protected]