Laureate Institute for Brain Research
​Adult studies (18-55) and General Info: 918.502.5100 | info@libr.net
​Teen studies (13-17): 918.502.5142 | info@libr.net
ABCD child study: 918.502.2223 | abcd@libr.net
  • Home
  • ABOUT
    • Mission
    • Leadership
    • Careers
    • Support LIBR
    • Directions
  • RESEARCH
    • Neuroimaging Facility
    • ABCD
    • Funding Sources
  • PEOPLE
    • All Staff
    • Faculty & Investigators >
      • Principal Investigators >
        • Robin Aupperle
        • Salvador Guinjoan
        • Sahib Khalsa
        • Martin Paulus
        • Jonathan Savitz
        • Ryan Smith
        • Jennifer Stewart
      • Associate Investigators >
        • Maria Ironside
        • Namik Kirlic
        • Masaya Misaki
        • Aki Tsuchiyagaito
        • Evan White
        • Haixia Zheng
      • Affiliate Investigators >
        • Hamed Ekhtiari
        • Rene Hurlemann
    • Administrative
    • Scientific
    • Clinical Assessment
    • Technology
    • In Memoriam >
      • Jerzy Bodurka
    • Alumni
    • Scientific Advisory Board
  • STUDIES
    • Ongoing Studies
    • NeuroMAP
    • PASO
    • TUTOUGH
    • Research Match
  • Resources
    • BARI Posters
    • Community Resources
    • COVID HERO
    • FAQ
  • NEWS
    • Current Events

Plasticity of Aversive Salience in Opioid Use Disorder (PASO)

Picture
The Plasticity of Aversive Salience in Opioid Use Disorder (PASO) study is a five year project funded by the National Institute on Drug Abuse (NIDA; grant # R01DA050677) to better understand the process of early recovery from opioid addiction (the first three months after entering treatment). People struggling with opioid addiction experience heightened stress, drug craving/urges, aversive bodily sensations, and negative emotions including depression, anxiety, pain, and suicidal thoughts when trying to quit drugs and stay abstinent. We want to understand how clinical symptoms, behavior, brain function, and physiology change during early recovery and predict who has success remaining abstinent the first three months post-treatment. We hope that knowledge from the PASO study will aid in the development of new intervention targets for opioid addiction. We have partnered with 12&12 Inc. and Women In Recovery to recruit individuals in their treatment programs for the PASO study.  

About 12 & 12 Inc.

12&12, Inc. is the largest Comprehensive Community Addiction Recovery Center in Oklahoma. At 12&12, our only focus is to help men and women battle the brain disease of addiction and co-occurring substance abuse/mental health disorders. Our complete continuum of care provides multiple levels of treatment including detoxification, intensive residential treatment, outpatient and intensive outpatient treatment, counseling, transitional living, and sober living.

For over 35 years, we have helped thousands of Oklahomans in the fight to get their lives back. Our service model is based on a multi-disciplinary approach that integrates medical oversight, psychiatry, nursing, counseling and case management.
​
Independently operated and located in the heart of Tulsa, we have Behavioral Health Care accreditation from the Joint Commission, and are certified by the Oklahoma Department of Mental Health and Substance Abuse Services (ODMHSAS) as a Comprehensive Community Care Addiction Recovery Center (CCARC). For more information on 12&12, Inc. visit www.12and12.org.

About Women in Recovery

Women in Recovery (WIR) is an intensive outpatient alternative for eligible women facing long prison sentences for non-violent drug-related offenses. Operated in partnership with the George Kaiser Family Foundation, WIR works closely with the criminal justice system and various community partners to ensure program participants receive supervision, substance abuse and mental health treatment, education, workforce readiness training and family reunification services. Benefits:
  • Strengthens individuals and families
  • Breaks the cycle of intergenerational incarceration
  • Helps women involved in the criminal justice system become productive, tax-paying citizens
  • Is more cost-effective than incarceration
  • Improves public safety
Addiction, abuse and poverty are factors that impact the vast majority of WIR participants. We help women conquer their drug addiction, recover from trauma and acquire the essential economic, emotional and social tools to build successful and productive lives. WIR is designed for women who are dedicated to changing their lives and becoming positive, contributing members of our community.

The PASO Team

Picture
Jennifer Stewart
Principal Investigator
​LIBR
Picture
Rajita Sinha
​Consultant, Yale University
Picture
Rayus Kuplicki
​Co-Investigator
​LIBR
Picture
Chrysantha Davis
​Study Coordinator
Picture
Martin Paulus
Co-Investigator
LIBR
Picture
Natosha Markham
Clinical Research Interviewer
Picture
Henry Yeh
​Consultant
​Kansas City Children’s Hospital
Picture
MaryKate Dykes
Research Specialist

Visit LIBR

6655 South Yale Ave. Tulsa, OK 74136
918.502.5100 | info@laureateinstitute.org

Get Connected

Picture
Picture
Picture
Picture
Picture
Careers  |  Compliance

© 2009-2022. All rights reserved
Laureate Institute for Brain Research



Website by Laureate Institute for Brain Research
© 2014. All rights reserved.

6655 South Yale Avenue
Tulsa, Oklahoma 74136-3326