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IN MEMORIAM

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Dr. Jerzy Bodurka Legacy Website

Dr. Jerzy Bodurka passed away on Friday, August 13, 2021. 
He was a pioneer and a world-renowned expert in the fields of magnetic resonance imaging (MRI) and functional MRI and enjoyed a storied scientific career and many prestigious awards. He worked as a staff scientist at the National Institutes of Health (NIH) and received the NIH Director's Award in 2007 for his advancements in MRI imaging technology. In 2009, he joined the Laureate Institute for Brain Research (LIBR) in Tulsa, OK, where he worked to build an international reputation in magnetic resonance imaging physics and its applications to improving mental health. 

He cared deeply about people – those in his group, in his work and in his family. He was a thoughtful and engaging collaborator who advocated for new researchers. He was a loving husband, father, brother, son, mentor and colleague with a knack for technology and tinkering – his wife and daughter joke that they always had a willing IT professional on call. He loved World War II history, space exploration, hiking, tennis, movies, walking with the family dog and most of all, his family.

In lieu of flowers, the family asks that you please consider donations to Laureate Institute for Brain Research to continue Jerzy's life's work in advancing interventions for mental health.

The Bodurka Laboratory (Archived 08/13/2021)

Jerzy Bodurka, Ph.D.

Chief Technology Officer
Director, MRI-EEG Facility
Laureate Institute for Brain Research

Associate Professor
Stephenson School of Biomedical Engineering, The University of Oklahoma
​
​Google Scholar Profile

Email: jbodurka@laureateinstitute.org | Phone: 918-502-5101


Our Research Approach

Dr. Bodurka's research focuses on three main areas:

(1)   Non-invasive, multimodal neuroimaging method development and applications for studying brain function including: structural and functional MRI (fMRI), real-time fMRI with neurofeedback, multimodal simultaneous electroencephalography (EEG) and fMRI brain imaging, real-time integration of fMRI and EEG data, simultaneous EEG and fMRI neurofeedback, EEG and fMRI hyperscanning.

(2)   Novel non-invasive brain neuromodulation and neuroenhancement approaches to better understand brain emotion regulation and social interactions in major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). Dr Bodurka's research has shown that the use of real-time fMRI neurofeedback during recall of positive emotions in patients with depression can normalize the neural activity of the amygdala and result in significant depression symptom relief.

(3)   Translational approaches to discover and research novel therapeutic strategies to improve treatments by training and recovering healthy function of brain networks, and to improve psychotherapy by determining the neural features of socially interacting individuals in MDD and PTSD.
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Research Program Highlights

Main Question
Can we use brain imaging and/or EEG to directly modulate brain areas that are important for treating anxiety or depression?

Approach
We use real-time fMRI feedback together with a focus on positive emotion tasks in patients with depression or PTSD to modulate the activation of the amygdala to improve symptoms.
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Current Findings
Depressed patients can learn to enhance amygdala activation to positive emotions, which is associated with a reduction in depressive symptoms.

Future Directions
We will determine whether this approach can also work with EEG, how long the symptom improvement will last, and whether other types of patients could benefit from real-time fMRI feedback.

Scientific Background

Dr. Bodurka has broad expertise in Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) physics. He received his doctorate degree in physics from the University of Nicolaus Copernicus in Torun, Poland and completed part of his postdoctoral training in NMR at the Department of Chemistry at Free University of Berlin, Germany.

​As a postdoctoral fellow at Medical College of Wisconsin, he received firm training in MRI technology and functional MRI (fMRI). As a Staff Scientist at the functional MRI Facility of the National Institute for Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), he was responsible for providing a state-of-the-art imaging environment for conducting advanced MRI and fMRI research.

In 2007, for his development of a Scalable Multi-Channel MRI Data Acquisition System, he received NIH’s Director Award for Advancements in MRI Parallel Imaging Technology. The advancements in MRI receiver and multi-element coils technologies allowed for major improvements in MRI signal-to-noise ratio and pushed spatial and temporal limits for both functional and anatomical imaging. He has also developed an advanced real-time software set-up allowing for conducting real-time fMRI with neurofeedback.

In 2009, Dr. Bodurka joined the newly established Laureate Institute for Brain Research (LIBR) to create a state-of-the-art MRI/fMRI/EEG neuroimaging facility and to a establish multimodal brain neuroimaging program with the overall purpose of advancing clinical research focused on mental disorders, with a broad research goal of advancing our understanding and characterization of brain abnormalities due to mental illness. 

Selected Publications

Connectome-wide investigation of altered resting-state functional connectivity in war veterans  with and without posttraumatic stress disorder. Misaki M, Phillips R, Zotev V, Wong CK, Wurfel BE, Krueger F, Feldner M, Bodurka J. Neuroimage: Clinical 17:285-296 (2018).
Randomized clinical trial of real-time fMRI amygdala neurofeedback for major depressive disorder: effects on symptoms and autobiographical memory recall. Young KD, Siegle GJ., Zotev V., Phillips R., Misaki M., Yuan H., Drevets WC., Bodurka J. American Journal of Psychiatry 174(8):748-755.  (2017).
Individual variations in nucleus accumbens associated with major depressive disorder symptoms. Misaki M, Suzuki H, Savitz J, Drevets WC, Bodurka J. Scientific Reports 6:21227 (2016).
Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: Association with sleep disturbance. Suzuki H, Savitz J, Teague K, Gandhapudi SK, Tan C, Misaki M, McKinney BA, Irwin MR, Drevets WC, Bodurka J. Brain Behav Immun 66:193-200 (2017).
Correlation between amygdala BOLD activity and frontal EEG asymmetry during real-time fMRI neurofeedback training in patients with depression. Zotev V, Yuan H, Misaki M, Phillips R, Young KD, Feldner MT, Bodurka J. Neuroimage Clin. 2016 Feb 12;11:224-38 (2016).
Automatic EEG-assisted retrospective motion correction for fMRI (aE-REMCOR). Wong CK, Zotev V, Misaki M, Phillips R, Luo Q, Bodurka J. Neuroimage 129:133-147 (2016).

Research Collaborators

Kent Teague, Ph.D.
University of Oklahoma- Tulsa
Hazem Refai, Ph.D.
University of Oklahoma- Tulsa
Samuel Chang, Ph.D.
University of Oklahoma- Tulsa
Peter Bandettini, Ph.D.
NIH/NIMH, Bethesda, MD
Matthew Feldner, Ph.D.
University of Arkansas
Frank Krueger, Ph.D.
George Mason University
Wenming Luh, Ph.D.
Cornell University
Michael Roy, M.D.
Uniformed Services University

Industry Collaborators

Patrick Britz, Ph.D.
​Brain Products GmBH, Germany
Patrick Ladden, Ph.D.
Nova Medical Inc., Wilmington, MA, USA
Scott Hinks, Ph.D.
GE Healthcare, Waukesha, WI, USA

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