H E L L O F R O M T U L S A, O K
GET TO KNOW LIBR
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WELCOME FROM THE PRESIDENT
Martin Paulus, M.D.
Scientific Director and President Mental health conditions remain among the most consequential challenges facing individuals, families, and communities. Although our understanding of the brain has advanced substantially, we still need better explanations for why mental health difficulties emerge, why they persist, and why people respond differently to treatment.
At the Laureate Institute for Brain Research, our mission is to improve mental health through neuroscience. Our investigators study how brain function, bodily physiology, behavior, and life experience interact to influence mental health and resilience. We use neuroimaging, biological measures, computational methods, and longitudinal clinical research to identify processes that are reliable, meaningful, and potentially modifiable. Our goal is not simply to generate new knowledge, but to translate discovery into better decisions about prevention, diagnosis, monitoring, and treatment. This work depends on close collaboration among researchers, clinicians, community partners, students, and—most importantly—the individuals who participate in our studies. We invite you to explore LIBR’s research and learn how our shared commitment to scientific rigor, innovation, and collaboration is helping shape a future in which mental health care is more effective, personalized, and accessible. |
MEET THE SCIENTISTS
Wes Thompson, Ph.D &
Chun Chieh Fan, M.D., Ph.D. Principal Investigators Population Neuroscience and Genetics (PNG) Center
The Population Neuroscience and Genetics (PNG) Center develops and applies cutting-edge analytic methods from multiple fields (e.g., causal inference, psychometrics, high-dimensional Bayesian inference) to address challenges under the rubric of Population Neuroscience. The multidisciplinary PNG investigative team extends an epidemiologically- and psychometrically-informed causal inference framework to neuroscientific research (existing in vivo human datasets from population registers and large-scale imaging genetic studies), developing and applying novel statistical and bioinformatic tools to critically examine the potential biases, causal pathways, and heterogeneity in longitudinal, lifespan neuropsychiatric outcomes. Dr. Thompson and Fan envisage the PNG Center as a hub for fellow researchers from multiple fields (e.g., neuroscience, genetics, epidemiology, data science, statistics, psychology and psychiatry), working together to move the field toward better analytic practice, more accessible research tools, and deeper understanding of heterogeneity of neuropsychiatric outcomes at the population level. With insight gained from vertical integration of whole-brain imaging analyses, population cohorts, and detailed molecular assays, they strive to get closer to discovering leverage points for improving psychiatric well-being. |
WHAT'S NEW & NOTEWORTHY
2025 LIBR Annual Report
The 2025 Laureate Institute for Brain Research (LIBR) Annual Report is now available to download via the link below. The report highlights the past year at LIBR, including a message from President and Scientific Director, Dr. Martin Paulus, updates on current research areas, and an overview of key initiatives and accomplishments. This year’s report also features progress in areas such as treatment-resistant depression, neuromodulation, and large-scale population studies, as well as continued efforts to integrate neuroscience, data science, and clinical research. Readers will also find information on collaboration, training programs, select publications, and opportunities to participate in research. We hope you enjoy this year’s publication and appreciate your continued interest in LIBR’s work to advance mental health through science in 2026 and beyond. |
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THE WILLIAM K. WARREN FOUNDATIONThe Laureate Institute for Brain Research opened May 1, 2009 and currently houses a multidisciplinary team of scientists and clinical research staff who apply neuroimaging, genetic, pharmacological and neuropsychological tools to investigate the biology of neuropsychiatric disorders. The Institute's creation was founded by The William K. Warren Foundation for the purpose of conducting studies aimed at developing more effective treatments or prevention strategies for these disorders. LIBR-sponsored research studies are led by scientists from diverse backgrounds, including physics, cognitive neuroscience, psychology, psychiatry, developmental neuroscience, computer science and genetics.
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