Ned H. Kalin, M.D., February 2, 2021

"The Childhood Risk to Develop Anxiety and Depression:  A Translational Neuroscience Approach"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Virtual Presentation via Zoom (email for link)
12:00 pm - 1:00 pm     Program

Ned H. Kalin, M.D. is Hedberg Professor and Chairman of the Department of Psychiatry at the University of Wisconsin School of Medicine and Public Health.  He is the Director of the HealthEmotions Research Institute and the Lane Neuroimaging Laboratory, a Professor in the Department of Psychology at the University of Wisconsin, and an affiliate scientist at the Wisconsin Reginal Primate Center and the Harlow Primate Laboratory.  He serves as the principal investigator for several ongoing NIH funded research projects and has published over 250 peer-reviewed articles related to the adaptive and maladaptive expression of emotion and anxiety, and the childhood risk to develop anxiety disorders and depression.  His research focuses on uncovering basic mechanisms that relate stress to the development of psychopathology and to understanding the mechanisms that cause some children to be vulnerable for the development of anxiety and depression.  The aim of his research is to develop novel, neuroscientifically-informed strategies for the treatment of anxiety disorders with a special focus on early life and preventive interventions for young children.  In addition to his research activities, he treats patients who suffer from anxiety and depression who are refractory to standard treatment.

Dr. Kalin earned his medical degree from Jefferson Medical School in Philadelphia, Pennsylvania, did his residency in the Department of Psychiatry at the University of Wisconsin, and a fellowship in Neuropsychopharmacology at the National Institute of Mental Health. Dr. Kalin is board certified by the American Board of Psychiatry and Neurology. He is a Fellow Emeritus of the American College of Neuropsychopharmacology and a fellow of the American College of Psychiatry. He has been recognized for numerous awards including the 1985 A.E. Bennett Award for basic science research in biological psychiatry, the 2005 Edward A. Strecker Award, the 2007 American College of Psychiatrists Award for research in mood disorders, the 2007 Gerald Klerman Senior Investigator Award, and the 2015 AnnaMonika Prize of the European College of Neuropsychopharmacology. In 2013 he was inducted as a Fellow in theAmerican Association for the Advancement of Science, and in 2015 he was elected as a member of the National Academy of Medicine. In 2017, Dr. Kalin was inducted as a Distinguished Life Fellow of the American Psychiatric Association. He has served as President of the International Society of Psychoneuroendocrinology and President of the Society of Biological Psychiatry, as a member of the National Advisory Mental Health Council and as Co-Editor for the international journal, Psychoneuroendocrinology. In 2019, Dr. Kalin was appointed as the Editor-in-Chief of the American Journal of Psychiatry.
Learning objectives: 

 1. Recognize early life risk factors to develop anxiety and depression.
 2. Describe brain alterations associated with childhood illness.
 3. Consider ideas about treatment informed by neuroscientific evidence.

Peter L. Strick, Ph.D., January 19, 2021

"The Neural Basis of the 'Brain-Body' Connection"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Virtual Presentation via Zoom (email for details) 
12:00 pm - 1:00 pm     Program

Peter L. Strick, Ph.D., Thomas Detre Professor and Chair, Department of Neurobiology; Scientific Director, University of Pittsburgh Brain Institute; Co-Director, Center for Neuroscience, University of Pittsburgh.

Peter L. Strick, Ph.D., received his B.A. (Biology, 1968) and Ph.D. (Anatomy, 1972) from the University of Pennsylvania. Then, he was a Staff Fellow in Edward V. Evarts’ Laboratory of Neurophysiology at NIMH (1972-1976). In 1976, Strick moved to the VA Medical Center, Syracuse, NY and the Departments of Neurosurgery and Physiology, SUNY-Upstate Medical Center. He was appointed George W. Perkins, III Memorial Professor in Neurosurgery (1988) and served as Acting President of the Central New York Research Corp. (1994-1996), and Interim Director of the Neuroscience Program at SUNY-Upstate (1997-1998).

In 2000, Strick moved to the University of Pittsburgh to become Co-Director, Center for the Neural Basis of Cognition and Professor, Departments of Neurobiology, Neurological Surgery, Physical Medicine & Rehabilitation, and Psychiatry. In 2007, Strick became the founding Director of the Systems Neuroscience Center at the University of Pittsburgh Medical School. In 2012, Strick was appointed the Thomas Detre Professor and Chair, Department of Neurobiology and co-director for the Center for Neuroscience. Strick also was appointed the founding Scientific Director of the University of Pittsburgh Brain Institute (2014-).

Strick co-founded the Neural Control of Movement Society (1990) and served as its Conference Co-Chair, Program Chair (1990-2007) and President (2007-2010). He was elected, Scientific Councilor (1996-2000) and Treasurer (1998-2000) of the Society for Neuroscience. He served as Section Editor (1986-1995) and then Editor-in-Chief, Journal of Neurophysiology (1995-2002), and he currently serves as Senior Editor, Cerebral Cortex (2003-) and on the PNAS Editorial Board (2016-).

Strick's major awards include the C.J. Herrick Award from the American Association of Anatomists (1979); Javits Neuroscience Investigator Award from NIH-NINDS (1986); Established Investigator Award from NARSAD (1995-1996); President's Award for Excellence and Leadership in Research, SUNY-Upstate Medical Center (1996); Senior Research Career Scientist Award from the Veterans Administration (1987-2015); University Distinguished Professor of Neurobiology (2011) and Chancellor's Distinguished Research Award, Senior Scholar, University of Pittsburgh (2013); Linné Lecture, Uppsala University (2017); Paul D. MacLean Award, American Psychosomatic Society (2018); Carnegie Science Award in the Life Sciences, (2018); and the Krieg Cortical Kudos Discoverer Award, Cajal Club (2019). Strick was elected to the American Academy of Arts and Sciences (2004) and to the National Academy of Sciences (2012).

Strick's research focuses on four major areas: the generation and control of voluntary movement by the motor areas of the cerebral cortex; the motor and cognitive functions of the basal ganglia and cerebellum; the neural basis for the mind-body connection; and unraveling the complex neural networks that comprise the central nervous system.

Learning objectives: 

 1. Identify the types of cortical areas that influence the function of the adrenal medulla.
 2. Identify the areas of the cerebral cortex that influence sympathetic output of the stomach.
 3. Identify the areas of the cerebral cortex that influence parasympathetic output to the stomach.
 

Yael Niv, Ph.D., November 18, 2020

"Latent Causes, Prediction Errors, and the Organization of Memory"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Virtual Presentation via Zoom (email for details)
12:00 pm - 1:00 pm     Program

Yael Niv received her MA in Psychobiology from Tel Aviv University and her PhD in Computational Neuroscience from the Hebrew University in Jerusalem, having conducted a major part of her thesis research at the Gatsby Computational Neuroscience Unit in UCL. She is currently a professor at Princeton University, at the Psychology Department and the Princeton Neuroscience Institute. Her lab's research focuses on the neural and computational processes underlying reinforcement learning and decision making, with a particular focus on how the cognitive processes of attention, memory and learning interact in constructing task representations that allow efficient learning and decision making. She is co-founder and co-director of the Rutgers-Princeton Center for Computational Cognitive Neuropsychiatry, where she is applying ideas from reinforcement learning to questions pertaining to psychiatric disorders within the new field of computational psychiatry. 

Learning objectives: 

1. Participants will understand what is a latent cause in learning theory.
2. Participants will understand why latent causes are useful in organizing memories.
3. Participants will understand the role of prediction errors in segmenting latent causes and, therefore, in organizing episodic memories

Jennifer Blackford, Ph.D., October 6, 2020

"What Causes Anxiety?  Building a Reverse Translational Model"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Virtual Presentation via Zoom 
12:00 pm - 1:00 pm     Program
Dr. Blackford is a Professor of Psychiatry and Behavioral Sciences and Vanderbilt University Medical Center, a Professor of Psychology at Vanderbilt University, and a Research Scientist at the Tennessee Valley VA. Dr. Blackford obtained her PhD in Developmental Psychology from Vanderbilt University, followed by training in neuroimaging and genetics, supported by a National Institute of Mental Health Mentored Career Development Award. Dr. Blackford's research is focused on identifying and characterizing the neurobiological basis of anxiety and the role of anxiety neurocircuitry in psychiatric disorders including PTSD, alcohol use disorders, and schizophrenia. She uses multi-modal and multi-level approaches. Multiple imaging methods are used to characterize brain structure, function, and connectivity. To provide a comprehensive assessment of anxiety, data are collected at the level of the brain, physiology, and behaviors. The long term goal of this research program is to use these discoveries to develop new prevention strategies for children at high-risk for developing psychiatric disorders and new treatments for individuals suffering with these disorders.
​
Learning objectives: 

 1. Compare the difference between fear and anxiety.
 2. State challenges for translating rodent findings to humans.
 3. Discuss the BNST's role in anxiety and addiction. 

Over the past weeks, we have experienced repeated events that are painful to watch, and that cannot be condoned with silence. It is all too obvious that people who look like me hurt people who do not look like me with the tacit assumption that there is no retribution. These events make me feel ashamed and guilty, feelings that are painful to be with and that my brain would prefer to suppress. These events have made me aware that there are many people who are struggling on a daily basis and are facing bodily harm, oppression, injustice, and disrespect. Violence against Black people has brought this struggle in focus, but these events are not limited to Blacks alone. There is an unfortunate history of violence and injustice against American Indian, Asian American, Hispanic American, and other minorities. Moreover, this struggle extends to one’s sexual orientations or one’s belief systems in contrast with the mainstream. One common element is the intolerance of what is different and the anger, aggression, and hate that emerges from this intolerance.
 
In science, we aim to observe, experiment, and draw conclusions from the facts.  However, science does not happen in a vacuum. It is done by people and – when it involves the human condition – it focuses on people. We have to ask ourselves, have the events that occurred on our streets also occurred in more subtle ways in our laboratories? Have people that look like me hurt people that do not look like me? The answer is yes, and this admission demands further evaluation. First, given certain circumstances, we are all capable of biased or racist thoughts, feelings, and actions. This is the source of pain experienced by those who see people of their group hurting those that are not part of their group. Second, we have to make an ongoing effort to openly work with these sentiments and to arrive at choices that will reduce the chance that we will hurt people who are different from us in the future. Third, we have to provide an opportunity for those who are the target of these injustices.  However, that also means we have to learn about their struggle, understand the particulars of the pain they are experiencing, and develop paths that will reduce those painful events within the context of science in the future. Fourth, curiosity and understanding have to win over ignorance and intolerance. We need to learn about our differences, understand how they influence our feelings, thoughts, and actions, and develop better explanations of the human conditions that we are interested in.
 
Outrage and anger over the events on our streets, laboratories, and other public or private places are not enough. It may even be a cage that will not allow us to understand why we are inflicting pain on others and how this increases all human suffering. Instead, open engagement with respect, interest, and love will help to develop the understanding that can be used to build new systems to reduce the pain of those in the minority. The situation is serious and calls for urgent and sustained engagement in finding new solutions. Scientists are problem solvers; we need to be thinking about our contribution to finding solutions to overcoming intolerance, anger, and aggression on the one hand and discover ways of healing the pain of those that have been the target of racism. We must work to build each other up and empower minorities in science rather than tearing people down.
 
To that end, we have started a workgroup that consists of individuals who work at LIBR to enhance the recognition that race and ethnicity play an important role to improve our scientific approach to solving mental health problems:
 
Aim 1: Increase the consideration of race/ethnicity when developing research questions, analysis plans, and assessments (e.g., including biological, sociocultural, economic variables).

• Goals:
  • Increase investigator and staff understanding and comfort level with research on race and ethnicity concerning neuroscience and mental/physical health 
  • Increase understanding and sensitivity to issues of race/ethnicity in the conduct of research.
• Actions: 
  • Establish a “Diversity in Mental Health and Neuroscience Research” lecture series for which we invite experts in related areas of research to present their work.
  • Establish a training seminar or reading group for all LIBR staff/faculty concerning issues of culture and diversity in the conduct of research 
  • Establish a community advisory board with standing and/or rotating membership to inform how we can make our research more relevant to individuals from diverse racial and ethnic backgrounds.

 
Aim 2: Increase the representation of under-represented minorities in the neuroscience and mental health research workforce.

• Goals:
  • Increase representation of researchers from under-represented minorities on our invited speaker lineup (WKW, Brown bags, Visiting Scientists).
  • Increase recruitment of under-represented minorities at all levels of employment and training (research assistants, students, staff scientists, investigators).
• Actions:
  • Ensure that advertisements for new positions are sent to universities and organizations with diverse students/members 
  • Establish Summer research opportunities for undergraduate and graduate students from underrepresented minorities. 

 
Aim 3: Enhance outreach efforts to and partnership with communities and organizations with diverse race/ethnicity representation.

• Goals:
  • Increase our understanding of how we can optimize our research to better answer questions of relevance to individuals from diverse race/ethnicity backgrounds.
  • Increase recruitment of participants from diverse race/ethnicity backgrounds.
• Actions:
  • Organize regular opportunities for LIBR employees to volunteer together with Tulsa communities and organizations. 
  • Identify organizations and clinics that we can partner with to support the recruitment of participants from diverse race/ethnicity backgrounds. 

Judson Brewer, M.D., Ph.D., March 3, 2020

"One Simple Ingredient for Habit Change:  Awareness"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
11:00 am - 11:45 am    Registration and Lunch, lunch stops being served at 11:45 - no exceptions
12:00 pm - 1:00 pm     Program
​
Jud Brewer MD PhD is the Director of Research and Innovation at the Mindfulness Center and associate professor in Behavioral and Social Sciences at the School of Public Health and Psychiatry at the Medical School at Brown University. He also is a research affiliate at MIT.

A psychiatrist and internationally known expert in mindfulness training for addictions, Brewer has developed and tested novel mindfulness programs for behavior change, including both in-person and app-based treatments for smoking, emotional eating, and anxiety. He has also studied the underlying neural mechanisms of mindfulness using standard and real-time fMRI, and source-estimated EEG, and is currently translating these findings into clinical use (see www.drjud.com for more information).

He has published numerous peer-reviewed articles and book chapters, presented to the US President’s Office of National Drug Control Policy, foreign Parliaments, trained US Olympic athletes and coaches, and foreign government ministers and has been featured on 60 minutes, at TED (4th most viewed talk of 2016 with over 14 Million views), in Time magazine (top 100 new health discoveries of 2013), Forbes, Businessweek, NPR, National Geographic, and the BBC among others. He is the author of The Craving Mind: from cigarettes to smartphones to love, why we get hooked and how we can break bad habits (New Haven: Yale University Press, 2017). Follow him on twitter @judbrewer.

Learning objectives: 
1. Understand how habits are formed and perpetuated.
2. Discuss how mindfulness can help us step out of our old habits.
3. Learn how mindfulness can change our default brain patterns.

Please register for the lunch/lecture by calling or emailing:
Lauren Haguewood
Phone (918) 494-6490
Email: lehaguewood@saintfrancis.com 

​Janet Treasure, M.D., Ph.D.
​February 4, 2020
" Translational Research in Anorexia;  Relevant Results for the Everyday Practice "

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
11:00 am - 11:45 am    Registration and Lunch, lunch stops being served at 11:45 - no exceptions
12:00 pm - 1:00 pm     Program
​
Janet Treasure, M.D., Ph.D., completed her medical degree and a PhD in Physiology at St. Thomas’ Medical School in London. For much of her career, Dr. Treasure specialized in the treatment of eating disorders at the Maudsley Hospital and in King’s College London. She has carried out extensive research - often collaboratively with patients and carers- which led to a greater understanding of, and better treatments for eating disorders. 

Dr. Treasure has trained over 40 PhD students who have implemented various aspects of translational psychiatry as part of their research training.  Many of these have progressed to hold important academic and clinical positions in eating disorders. She worked collaboratively with other international centres and has authored over 600 scientific articles. 
As well as writing professional texts, Dr. Treasure co-produced self-care interventions (in books and e-health formats) for people affected by eating disorders and their careers and received many awards for her research. 
​
Learning objectives: 

 1. Review the cognitive interpersonal model.
 2. Discuss predisposing and precipitating factors.
 3. Understand how can we target perpetuating factors in treatment. 

Peter Kalivas, Ph.D., November 19, 2019
"Using the Neuroscience of Willpower to Treat Addiction"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
11:00 am - 11:45 am    Registration and Lunch, lunch stops being served at 11:45 - no exceptions
12:00 pm - 1:00 pm     Program

Peter Kalivas, Ph.D. is a neuropharmacologist best known for his work to elucidate the brain molecules and neurocircuitry that underlie drug addiction.  His research has identified new brain mechanisms that have become potential pharmacotherapeutic targets for treating addiction in clinical trials. He is a Distinguished University Professor and founding Department Chair of Neuroscience at the Medical University of South Carolina in Charleston. He was President of the American College of Neuropsychopharmacology in 2014.  He received his Ph.D. in Pharmacology from the University of Washington in Seattle in 1980, and during a postdoctoral fellowship at the University of North Carolina in Chapel Hill (1980-82) he became oriented towards the role that brain circuitry plays in the regulating behavior. In his first faculty position at Louisiana State University in New Orleans (1982-84) and during a more extensive tenure at Washington State University (1984-98) he came to career research focus on the cellular and molecular underpinnings of the brain circuits mediating addiction. 
​
Learning objectives:  

1. Understand the role of will power in regulating addictive behavior.
2. Understand the neurobiology of how drugs of abuse alter brain circuits to weaken will power.
3. Understand the latest thinking and experimental treatments for how to manipulate will power circuitry to promote abstinence.

Read Montague, Ph.D.

"Tilting Back to Neurobiology: Computational Psychiatry in an Invasive Setting"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
10:00 am - 10:45 am    Registration and Brunch, brunch stops being served at 10:45 - no exceptions
11:00 am - 12:00 pm    Program

Read Montague, Ph.D. is the director of the Human Neuroimaging Lab and Computational Psychiatry Unit at the Fralin Biomedical Research Institute at VTC in Roanoke, Virginia. Dr. Montague’s work focuses on computational neuroscience – the connection between physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody. His early theoretical work focused on the hypothesis that dopaminergic systems encode a particular kind of computational process, a reward prediction error signal, similar to those used in areas of artificial intelligence like optimal control. In pursuit of testing these ideas in humans, Montague founded the Human Neuroimaging Lab at Baylor College of Medicine in Houston, Texas, and pursued functional neuroimaging experiments analogous to those used in other model species.

In 2011, Dr. Montague received a Principal Research Fellowship from The Wellcome Trust and became a principal at The Wellcome Centre for Neuroimaging at University College London (UCL). At UCL, he also serves as adjunct faculty at the Gatsby Computational Neuroscience Unit and participating faculty member of the University College London/Max Planck Institute Centre for Computational Psychiatry and Ageing.

He is actively engaged in translating computational neuroscience into the domain of mental health through work in Computational Psychiatry. His group has recently pioneered new approaches to sub-second neurotransmitter measurements in conscious humans. Over the past decade, he was a member of the MacArthur Foundation Network on Neuroscience and Law with a particular interest in the mental states project(s). His laboratory uses theoretical, computational and experimental approaches to the problems of mental health and its derangement by disease and injury. Work in the laboratory is supported by the National Institutes of Health, National Science Foundation, The Kane Family Foundation, Autism Speaks, The MacArthur Foundation, The Dana Foundation and The Wellcome Trust.

Learning Objectives:
1. Discuss how two-party games of monetary exchange between humans help to identify traditionally-defined psychopathology groups.
2. Learn about new extensions to electrochemistry now available for use in conscious humans.
3. Understand that connection between dopamine and serotonin signaling and their putative computational function in reward learning.

Richard J. Davidson, Ph.D.

"Cultivating Well-Being: Perspectives from Affective and Contemplative Neuroscience"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
11:00 am - 11:45 am    Registration and Lunch, lunch stops being served at 11:45 - no exceptions
12:00 pm - 1:00 pm     Program

Dr. Richard Davidson received his Ph.D. from Harvard University and has been at The University of Wisconsin Madison since 1984. He has published more than 400 articles, numerous chapters and reviews and edited 14 books. He is the author (with Sharon Begley) of The Emotional Life of Your Brain published by Penguin in 2012. He is co-author with Daniel Goleman of Altered Traits: Science Reveals How Meditation Changes Your Mind, Brain and Body, published by Penguin Books in 2017. He is the recipient of numerous awards for his research and was the year 2000 recipient of the most distinguished award for science given by the American Psychological Association – the Distinguished Scientific Contribution Award. He was the founding co-editor of the new American Psychological Association journal EMOTION and is past-president of the Society for Research in Psychopathology and of the Society for Psychophysiological Research. Dr. Davidson’s research is broadly focused on the neural bases of emotion and emotional style and methods to promote human flourishing including meditation and related contemplative practices. His studies have included persons of all ages from birth though old age and have also included individuals with disorders of emotion, such as mood and anxiety disorders and autism, as well as expert meditation practitioners with tens of thousands of hours of experience. His research uses a wide range of methods including different varieties of MRI, positron emission tomography, electroencephalography and modern genetic and epigenetic methods.

Learning Objectives
1. Identify four important constituents of well-being.
2. Discuss the brain circuits that underlie these constituents.
3. Understand the different forms of meditation practice that impact well-being and its neural bases.

Nora Volkow, M.D., Director of the National Institute on Drug Abuse, NIH

"Drug Addiction as a Disease of the Human Brain"
12:00 pm - 1:00 pm
Laureate Psychiatric Clinic and Hospital Conference Center 

Nora Volkow M.D., is Director of the National Institute on Drug Abuse at the National Institutes of Health (NIH). Over the past 30 years, she has published more than 770 peer-reviewed articles, more than 95 book chapters, edited four books on brain imaging and addiction and co-edited an Encyclopedia on Neuroscience. She has received multiple awards including membership in the National Academy of Medicine in 2000 and the International Prize for Science from the French Institute of Health and Medical Research in 2009. She was named one of Time magazine’s “Top 100 People Who Shape Our World”, “One of 20 People to Watch”, by Newsweek magazine and “Innovator of the Year” by U.S. News & World Report. Her work as a researcher and as a leader has been instrumental in transforming the paradigm of drug addiction from that of a behavioral choice to that of a treatable brain disease.

Marc Schuckit, M.D.

"A 35-Year Longitudinal Study of Risk Factors for Alcoholism"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
10:00 am - 10:45 am    Registration and Brunch, brunch stops being served at 10:45 - no exceptions
11:00 am - 12:00 pm    Program

Dr. Marc A. Schuckit is a distinguished Professor of Psychiatry at the University of California, San Diego. His work regarding substance use and related disorders has focused primarily on risk factors for developing heavy drinking and alcohol use disorders (AUDs); how genetic and environmental contributors toward this risk can operate through a low level of response (low LR) to alcohol and how such data can be used to help prevent alcohol-related problems; fMRI-based brain mechanisms that contribute to this low response; and longitudinal studies of individuals at high risk for AUDs. He has also published about the development of diagnostic criteria for substance use disorders (SUDs) overall. Dr. Schuckit developed the concept of an AUD risk through the low level response (LR) to alcohol, established methodologies and designs for assessing the construct and tested LR across populations (e.g., adolescents, adults, females, males) and across generations in the U.S. and U.K. The causes of heavy drinking and alcohol problems are many and identifying these is an important endeavor. Dr. Schuckit has maintained a strong interest in issues related to alcohol and other substance-related disorders, both from the standpoint of diagnosis as chair of the DSM-IV and member of the DSM-5 SUD workgroups and by producing overviews of clinically relevant topics as published in the New England Journal of Medicine and Lancet, including overviews of delirium tremens, treatments for AUDs and the treatment of opioid use disorders.

Learning Objectives:
1. Understand the role of genetic contributors to alcoholism.
2. Learn about the role of the low level of response to alcohol as an endophenotype enhancing the alcoholism risk.
3. Discuss how such risk factors can be used to help prevent heavy drinking and alcohol problems.

Carlos A. Zarate, M.D.

"Deconstructing the Neurobiology of Mood Disorders using Rapid Acting Antidepressant and Antisuicidal Ideation Interventions as a Bridge to Novel Therapeutics"

William K. Warren, Jr.  Frontiers in Neuroscience Lecture 
Laureate Psychiatric Clinic and Hospital Conference Center 
11:00 am - 11:45 am    Registration and Lunch, lunch stops being served at 11:45 - no exceptions
12:00 pm - 1:00 pm     Program

Carlos A. Zarate, M.D. is Chief of the Experimental & Therapeutics Branch and of the Section on Neurobiology and Treatment of Mood and Anxiety Disorders, and Senior Tenured Clinical Investigator, Division Intramural Research Program, National Institute of Mental Health, Clinical Professor of Psychiatry and Behavioral Sciences, George Washington University and Professor of Psychiatry and Behavioral Sciences, Howard Medical School.
​
Carlos A. Zarate, M.D. is Chief Experimental Therapeutics & Pathophysiology Branch and of the Section on Neurobiology and Treatment of Mood and Anxiety Disorders, Division Intramural Research Program, National Institute of Mental Health. Dr. Zarate completed his residency training in psychiatry at the Massachusetts Mental Health Center/Brockton VAMC division. He later completed a fellowship in Clinical Psychopharmacology at McLean Hospital of the Consolidated Department of Psychiatry, Harvard Medical School and remained on staff at McLean Hospital as the Director of the Bipolar and Psychotic Disorders Outpatient Services. From 1998 to 2000 Dr. Zarate was the Chief of the Bipolar and Psychotic Disorders Program at the University of Massachusetts Medical School. In 2001, he joined the Mood and Anxiety Disorders Program at NIMH. His achievements and awards include the Ethel-DuPont Warren Award and Livingston Awards, Consolidated Department of Psychiatry, Harvard Medical School; Outstanding Psychiatrist Research Award, Massachusetts Psychiatric Association; Program for Minority Research Training in Psychiatry, APA; the National Alliance for Research on Schizophrenia and Depression Young Investigator Award; National Alliance for Research on Schizophrenia and Depression Independent Investigator Award; the National Institutes of Health Director’s Award Scientific/Medical, the 2011 Brain & Behavior Research Foundation Award for Bipolar Mood Disorder Research, the 2013 National Institute of Health Director’s Award—Scientific/Medical Achievement and Mogens Schou Research Award: Bipolar Disorder and the Simon-Bolivar Award American Psychiatric Association; 2015 Ruth L. Kirschtein Mentoring Award NIH and the Astute Clinician Lecture Award, NIH. Dr. Zarate is a fellow of the American College of Neuropsychopharmacology and member of the Society of Biological Psychiatry and the Society for Neuroscience. Dr. Zarate’s research focuses on the pathophysiology and development of novel therapeutics for treatment-resistant mood disorders as well as the study of biomarkers and neural correlates of treatment response.

Learning objectives: 

1. Discuss the causes of treatment-resistant depression.
2. Become familiar with research on treatment-resistant depression, particularly with ketamine and other glutamatergic modulators.
3. To understand research on biomarkers of treatment response.

 
For Physicians: CME credit will be given.

For Psychologists: The Oklahoma State Board of Examiners of Psychologists, the American Psychological Association and the Oklahoma Psychological Association recognizes AMA PRA Category 1 credit™.  

For Social Workers: This event has been approved by the Oklahoma State Board of Licensed Social Workers for 1 hour Category 1Clinical.  (CEP Number - 20150007)

For LPCs and LMFTs: An application has been made to the State Board of Behavioral Health Licensure (BBHL) for 1 hour of CE.

For CADCs and LADCs: Laureate Psychiatric Clinic and Hospital, Tulsa, Oklahoma, is accredited as a provider of continuing chemical dependency education by the State of Oklahoma - Board of Licensed Alcohol and Drug Counselors for 1 hour of CE.                                     
REGISTER TO ATTEND!

To register, email:  Lauren Haguewood at lehaguewood@saintfrancis.com

Distinguished Speakers
​
Jason Beaman, D.O. 
Chair, Department of Psychiatry and Behavioral Sciences OSUCHS

Gerard Clancy, M.D.
President, University of Tulsa

Sarah W. Feldstein Ewing, Ph.D. 
Oregon Health & Science University, Director, Adolescent Behavioral Health Clinic

Francesca Filbey, Ph.D.
University of Texas at Dallas, School of Behavioral and Brain Science

Scott Grantham, M.D. 
Medical Director, Laureate Psychiatric Clinic and Hospital

Kent Hutchinson, Ph.D. 
University of Colorado Boulder, The Center for Health and Addiction: Neuroscience, Genes, and Environment

Martin Paulus, M.D.
Scientific Director, Laureate Institute for Brain Research

Susan Tapert, Ph.D.
University of California at San Diego, Department of Psychiatry

Terri White, M.S.W
Commissioner, Office of Mental Health and Substance Abuse

Accreditation Statements:
​
CADC’s and LADC’s: Saint Francis Health System is an approved provider of continuing education programs for CADC’s and LADC’s through the Oklahoma Board of Licensed Alcohol and Drug Counselors and has approved this program for (5.5 hours)

LPCS/LMFTs: An approval request has been sent into the State Board of Behavioral Health Licensure (BBHL) for 5.5 hours of CE.

Physicians: Saint Francis Health System is accredited by the Oklahoma State Medical Association to sponsor continuing medical education for physicians
Saint Francis Health System designates this live activity for a maximum of 5.5 AMA PRA Category 1 credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Psychologists: The Oklahoma State Board of Examiners of Psychologists, the American Psychological Association and the Oklahoma Psychological Association recognizes this event, Cannabis: What we have Learned through Scientific Research at TU Lorton Center on January 17, 2018 for 5.5 AMA PRA Category 1 Credit. Saint Francis Health System is an Accredited through OSMA.

Social Workers: This event, “Cannabis: What we have Learned through Scientific Research” at TU Lorton Center on January 17, 2018 has been approved by the Oklahoma State Board of Licensed Social Workers for 5.5 hours Category 1 Clinical. (CEP Number- 20190007)
​